IPICYT
_
Investigación

>

Biología Molecular

>

Datos Curriculares

Datos Curriculares

Dr. Alejandro De Las Peñas Nava

Investigador Titular "C"

Integrante del SNI. Nivel 2

División de Biología Molecular

cano@ipicyt.edu.mx

Fax:

+52 (444) 834-2010

Ext.

2039

Tel.

+52 (444) 8342000

Selección de artículos de investigación


Publicaciones en el Science Citation Index

1.- Guadalupe Gutierrez-Escobedo, Norma Vazquez-Franco, Ana Lopez-Marmolejo, Gabriel Luna-Arvizu, Israel Cañas-Villamar, Irene Castaño-Navarro, Alejandro De Las Peñas "Characterization of the Trr / Trx system in the fungal pathogen Candida glabrata.". FUNGAL GENETICS AND BIOLOGY . 2023;

166

2.- Norma Vázquez-Franco, Guadalupe Gutiérrez-Escobedo, Alejandro Juárez-Reyes, Emmanuel Orta-Zavalza, Irene Castaño, Alejandro De Las Peñas "Candida glabrata Hst1-Rfm1-Sum1 complex evolved to control virulence-related genes". FUNGAL GENETICS AND BIOLOGY . 2022;

159

3.- Juan Ernesto López-Ramos, Elihú Bautista, Guadalupe Gutiérrez-Escobedo, Gabriela Mancilla-Montelongo, Irene Castaño, Marco Martín González-Chávez and Alejandro De Las Peñas "Analisis of volatile molecules present in the secretome of the fungal pathogen Candida glabrata". MOLECULES . 2021;

26(13) : 3831

4.- Guadalupe Gutiérrez-Escobedo, Oscar Hernández-Carreón, Brenda Morales-Rojano, Brenda Revuelta-Rodríguez, Norma Vázquez-Franco, Irene Castaño, Alejandro De Las Peñas "Candida glabrata peroxiredoxins, Tsa1 and Tsa2, and sulfiredoxin, Srx1, protect against oxidative damage and are necessary for virulence". FUNGAL GENETICS AND BIOLOGY . 2020;

135

5.- Eunice López-Fuentes, Guadalupe Gutiérrez-Escobedo, Bea Timmermans, Patrick Van Dijck, Alejandro De Las Peñas and Irene Castaño "Candida glabrata¿s genome plasticity confers a unique pattern of expressed cell wall proteins https://doi.org/10.3390/jof4020067 ". JOURNAL OF FUNGI . 2018;

4(2) 67 : 2-16

6.- Eunice López-Fuentes, Grecia Hernández-Hernández, Leonardo Castanedo, Guadalupe Gutiérrez-Escobedo, Katarzyna Oktaba, Alejandro De Las Peñas and Irene Castaño "Chromatin Loop Formation Induced by a Subtelomeric Protosilencer Represses EPA genes in Candida glabrata". GENETICS . 2018;

210 : 113-128

7.- Osney Leiva-Peláez, Guadalupe Gutiérrez-Escobedo Eunice López-Fuentes, José Cruz-Mora, Alejandro De Las Peñas, Irene Castaño "Molecular characterization of the silencing complex SIR in Candida glabrata hyperadherent clinical isolates https://doi.org/10.1016/j.fgb.2018.05.005". FUNGAL GENETICS AND BIOLOGY . 2018;

118 : 21-31 (en impresión (aceptado))

8.- Gehenna Guerrero-Serrano, Leonardo Castanedo, Gema R. Cristóbal-Mondragón, Javier Montalvo-Arredondo, Lina Riego-Ruiz, Alexander DeLuna, Alejandro De Las Peñas, Irene Castaño, Mónica R. Calera, Roberto Sánchez-Olea "Npa3/ScGpn1 carboxy-terminal tail is dispensable for cell viability and RNA polymerase II nuclear targeting but critical for microtubule stability and function.". BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH . 2017;

1864(3) : 451- 462

9.- A. Patron-Soberano, B. P. Núñez-Luna, S. Casas-Flores, A. De las Peñas, R. B. Domínguez-Espíndola, V. Rodríguez-González "Photoassisted inactivation of Escherichia coli bacteria by silver functionalized titanate nanotubes, Ag/H2Ti2O5.H2O". PHOTOCHEMICAL & PHOTOBIOLOGICAL SCIENCES . 2017;

16 : 854-860

10.- Karina Robledo-Marquez, Guadalupe Gutiérrez-Escobedo, Patricia Yáñez-Carrillo, Yamile Vidal-Aguiar, Marcela Briones-Martín-del-Campo, Emmanuel Orta-Zavalza, Alejandro De Las Peñas, Irene Castaño "Candida glabrata encodes a longer variant of the mating type (MAT) alpha2 gene in the mating type-like MTL3 locus, which can form homodimers. http://dx.doi.org/10.1093/femsyr/fow082". FEMS YEAST RESEARCH . 2016;

16(7)

11.- David Torres-Tirado, Maureen Knabb, Irene Castano, Araceli Patrón-Soberano, Alejandro De Las Penas and Rafael Rubio "Candida glabrata inhibits flow sense and cardiac agonist-response by binding to glycosylated and lectinic receptors on coronary endothelial luminal membrane.". AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY . 2016;

310 : 24-32

12.- Gabriela Pérez-Flores, Cesar Hernández-Silva, Guadalupe Gutiérrez-Escobedo, Alejandro De Las Peñas, Irene Castaño, Jorge Arreola, Patricia Pérez-Cornejo "P2X7 from j774 murine macrophages acts as a scavenger receptor for bacteria but not yeast. doi.org/10.1016/j.bbrc.2016.11.027". BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS . 2016;

48 : 19-24 (en impresión (aceptado))

13.- Patricia Yáñez-Carrillo, Emmanuel Orta-Zavalza, Guadalupe Gutiérrez-Escobedo, Araceli Patrón-Soberano, Alejandro De Las Peñas, Irene Castaño "Expression vectors for C-terminal fusions with fluorescent proteins and epitope tags in Candida glabrata.". FUNGAL GENETICS AND BIOLOGY . 2015;

80 : 43-52

14.- Alejandro De Las Peñas, Jacqueline Juárez-Cepeda, Eunice López-Fuentes, Marcela Briones-Martín-del-Campo, Guadalupe Gutiérrez-Escobedo and Irene Castaño "Local and regional silencing in Candida glabrata: consequences for adhesion and response to stress doi: 10.1093/femsyr/fov056". FEMS YEAST RESEARCH . 2015;

15(6) : 1-9

15.- Jacqueline Juárez-Cepeda, Emmanuel Orta-Zavalza, Jorge Arreola-Gómez, Gloria Patricia Pérez-Cornejo, Carmen Yudith Hernández-Carballo, Guadalupe Gutiérrez-Escobedo, Irene Castaño and Alejandro De Las Peñas "The EPA2 adhesin encoding gene is responsive to oxidative stress in the opportunistic fungal pathogen Candida glabrata. DOI 10.1007/s00294-015-0473-2". CURRENT GENETICS . 2015;

473

16.- Marcela Briones-Martin-del-Campo, Emmanuel Orta-Zavalza, Israel Cañas-Villamar, Guadalupe Gutiérrez-Escobedo, Jacqueline Juárez-Cepeda, Omar Arroyo-Helguera, Irene Castaño and Alejandro De Las Peñas "The superoxide dismutases of Candida glabrata protect against oxidative damage and are required for lysine biosynthesis, DNA integrity and chronological life survival.". MICROBIOLOGY-SGM . 2015;

161 : 300 - 310

17.- Emmanuel Orta-Zavalza, Gehenna Guerrero-Serrano, Guadalupe Gutiérrez-Escobedo, Israel Cañas-Villamar, Jacqueline Juárez-Cepeda, Irene Castaño and Alejandro De Las Peñas "Local silencing controls the oxidative stress response and the multidrug resistance in Candida glabrata". MOLECULAR MICROBIOLOGY . 2013;

88(6) : 1135-1148

18.- Guadalupe Gutiérrez-Escobedo, Emmanuel Orta-Zavalza, Irene Castaño, Alejandro De Las Peñas "Role of glutathione in the oxidative stress response in the fungal pathogen Candida glabrata". CURRENT GENETICS . 2013;

59 : 91-106

19.- Verónica Martínez-Jiménez, Candy Y. Ramírez-Zavaleta, Emmanuel Orta-Zavalza, Gabriel Díaz de León, Guadalupe Gutiérrez-Escobedo, Alfredo Ponce de León, José Sifuentes-Osornio, Miriam Bobadilla del Valle, Alejandro De Las Peñas and Irene Castaño "Sir3 Polymorphisms in Candida glabrata Clinical Isolates". MYCOPATHOLOGIA . 2013;

175(4) : 207-219

20.- Verónica Gallegos-García, Shih-Jung Pan, Jacqueline Juárez-Cepeda, Candy Y. Ramírez-Zavaleta, Marcela Briones Martin-del-Campo, Verónica Martínez-Jiménez, Irene Castaño, Brendan Cormack, and Alejandro De Las Peñas "A Novel Downstream Regulatory Element Cooperates With the Silencing Machinery to Repress EPA1 Expression in Candida glabrata". GENETICS . 2012;

190 : 1 - 13

21.- Alejandro Juárez-Reyes, Candy Y. Ramírez-Zavaleta, Luis Medina-Sánchez, Alejandro De Las Peñas and Irene Castaño "A protosilencer of subtelomeric gene expression in Candida glabrata with unique properties". GENETICS . 2012;

190(1) : 101-111 Número de citas: 1

22.- Arroyo-Helguera Omar, De Las Peñas Alejandro and Irene Castaño "Occurrence of killer Candida glabrata clinical isolates". BRAZILIAN JOURNAL OF MICROBIOLOGY . 2012;

43(3) : 880-887

23.- Ramírez-Zavaleta Candy Y., Salas-Delgado Griselda E., De Las Peñas Alejandro and Castano Irene "Subtelomeric silencing of the MTL3 locus of Candida glabrata requires yKu70, yKu80 and Rif1 proteins". EUKARYOTIC CELL . 2010;

9(10) : 1602-1611 Número de citas: 2

24.- Lavaniegos-Sobrino María Teresa, Ramírez-Zavaleta Candy Y., Ponce de León Alfredo, Sifuentes-Osornio José, Bobadilla-del Valle Miriam, Rangel-Cordero Andrea, De Las Peñas Alejandro and Castaño Irene "Genotyping of the MTL loci and susceptibility to two antifungal agents of Candida glabrata clinical isolates". MEMORIAS DO INSTITUTO OSWALDO CRUZ . 2009;

104(5) : 775-782

25.- Mayra Cuéllar-Cruz Irene Castaño, Omar Arroyo-Helguera, Alejandro De Las Peñas1 "Oxidative stress response to menadione and cumene hydroperoxide in the opportunistic fungal pathogen Candida glabrata". MEMORIAS DO INSTITUTO OSWALDO CRUZ . 2009;

104 : 649-654 Número de citas: 3

26.- Mayra Cuéllar Cruz, Marcela Briones Martin del Campo, Israel Cañas Villamar, Javier Montalvo Arredondo, Lina Riego Ruiz, Irene Castaño, and Alejandro De Las Peñas "High resistance to oxidative stress in the fungal pathogen Candida glabrata is mediated by the single catalase, Cta1p, and controlled by the transcription factors Yap1p, Skn7p, Msn2p and Msn4p.". EUKARYOTIC CELL . 2008;

7 : 814 - 825 Número de citas: 24

27.- Lluvia L. Rosas-Hernández, Alejandro Juárez-Reyes, Omar E. Arroyo-Helguera, Alejanadro De Las Peñas, Shih-Jung Pan, Brendan P. Cormack and Irene Castaño "yKu70/80 and Rif1 regulate silencing differentially at telomeres in Candida glabrata". EUKARYOTIC CELL . 2008;

7 (12) : 2168-2178 Número de citas: 11

28.- Renée Domergue, Irene Castaño, Alejandro De Las Peñas, Margaret Zupancic, Virginia Lockatell, J. Richard Hebel, David Johnson, Brendan P. Cormack. "Nicotinic Acid Limitation Regulates Silencing of Candida Adhesins During UTI". SCIENCE . 2005;

308 : 866-870 Número de citas: 80

29.- Irene Castaño, Rupinder Kaur, Shihjung Pan, Robert Cregg, Alejandro De Las Peñas, Nini Guo, Matt Biery, Nancy Craig, and Brendan P. Cormack. "Tn-7-based genome¿wide random insertional mutagenesis of Candida glabratra.". GENOME RESEARCH . 2003;

13 : 905-915 Número de citas: 29

30.- Alejandro De Las Peñas, Shih-Jung Pan, Irene Castaño, John Adler, Robert Cregg and Brendan Cormack "Virulence-related surface glycoproteins in the yeast pathogen Candida glabrata are encoded in sub-telomeric clusters and subject to RAP1-and SIR-dependent transcriptional silencing.". GENES & DEVELOPMENT . 2003;

17 : 2245-2258 Número de citas: 103

31.- Zhenghe Wang, Irene B. Castaño, Alejandro De Las Peñas, Carrie Adams, Michael F. Christman. "Pol kappa: a DNA required for sister chromatid cohesion.". SCIENCE . 2000;

289 : 774-779 Número de citas: 146

32.- Beck BJ; Connolly LE; De Las Peñas A; Downs DM. "Evidence that rseC, a gene in the rpoE cluster, has a role in thiamine synthesis in Salmonella typhimurium.". JOURNAL OF BACTERIOLOGY . 1997;

179 : 6504-6508 Número de citas: 26

33.- De Las Peñas A; Connolly L; Gross CA. "Sigma E is an essential sigma factor in Escherichia coli.". JOURNAL OF BACTERIOLOGY . 1997;

179 : 6862-6864 Número de citas: 100

34.- Connolly L; De Las Peñas A; Alba BM; Gross CA. "The response to extracytoplasmic stress in Escherichia coli is controlled by partially overlapping pathways.". GENES & DEVELOPMENT . 1997;

11 : 2012-2021 Número de citas: 62

35.- De Las Peñas A; Connolly L; Gross CA "The sigmaE -mediated response to extracytoplasmic stress in Escherichia coli is transduced by RseA and RseB, two negative regulators of sigmaE.". MOLECULAR MICROBIOLOGY . 1997;

24 : 373-385 Número de citas: 169

36.- Rouvière PE; De Las Peñas A; Mecsas J; Lu CZ; Rudd KE; Gross CA "rpoE, the gene encoding the second heat-shock sigma factor, sigma E, in Escherichia coli.". EMBO JOURNAL . 1995;

14 : 1032-1042 Número de citas: 202

37.- Vázquez M; Dávalos A; De Las Peñas A; Sánchez F; Quinto C. "Novel organization of the common nodulation genes in Rhizobium leguminosarum bv. phaseoli strains". JOURNAL OF BACTERIOLOGY . 1991;

173 : 1250-1258 Número de citas: 46

Publicaciones en otros índices internacionales

1.- Claire Lacombe, Estefania Aleman-Navaro, Thierry Drujon, , Lorena Elizabeth Fajardo Brigido, Yannick Fleury, Christophe Piesse, Guadalupe Gutiérrez-Escobedo, Alejandro De Las Peñas, Irene Castano, Yvonne Rosenstein and Constance Auvynet "Characterization of a New Immunosuppressive and Antimicrobial Peptide, DRS-DA2, Isolated from the Mexican Frog, Pachymedusa dacnicolor". International Journal of Inflammation . 2024;

2024 : 2205864

2.- Héctor Nájera-Rivera , Ana Rodríguez-Cortez , María Anaya-Santillán , Efrén Díaz-Aparicio Ariadna Ramos-Rodríguez , Irlanda Siliceo-Cantero , Norma Vázquez-Franco , Erik Nieto-Patlán Alejandro De Las Peñas , Liliana Valdés-Vázquez, Laura Cobos-Marin "Multiplex assay for the simultaneous detection of antibodies against small ruminant lentivirus, Mycobacterium avium subsp. paratuberculosis, and Brucella melitensis in goats". Veterinary World . 2023;

16 : 704-710

3.- Bea Timmerman, Alejandro De Las Peñas, Irene Castaño and Patrick Van Dijck "Adhesins in Candida glabrata. doi:10.3390/jof4020060". Journal of Fungi . 2018;

4 : 2-16

4.- Rebecca E. Zordan, Yuxia Ren, Shih‐Jung Pan, Giuseppe Rotondo, Alejandro De Las Peñas, Joseph Iluore, Brendan P. Cormack "Expression plasmids for use in Candida glabrata". G3:Genes, Genomes, Genetics . 2013;

3 : 1675 - 1686

Sube