Dr. Antonio De León Rodríguez

Investigador Titular "C"

Integrante del SNI. Nivel 3

División de Biología Molecular

aleonr@ipicyt.edu.mx

Selección de artículos de investigación

Publicaciones en el Science Citation Index

1.- Ornelas-Salas JT, Tapia-Picazo JC, De Leon-Rodriguez A "Tracing of di-ethylhexyl phthalate in the tequila production process". FOODS . 2024;

13(334) : 1-14

2.- Calva Cruz OJ, Ovando-Vázquez C, De León-Rodriguez A, Veana F, Espitia-Rangel E, Treviño S, Barba de la Rosa AP "Dietary Supplementation with Popped Amaranth Modulatesthe Gut Microbiota in Low Height-for-Age Children: ANonrandomized Pilot Trial". FOODS . 2023;

12 : 2760

3.- Velarde-Salcedo AJ, De León-Rodríguez A, Calva Cruz OJ, Balderas-Hernández VE, De Anda Torres S, Barba de la Rosa AP "Extraction of bioactive compounds from Rubus idaeus waste by maceration and supercritical fluids extraction: the recovery of high added-value compounds". INTERNATIONAL JOURNAL OF FOOD SCIENCE AND TECHNOLOGY . 2023;

4.- Torres-Pacheco LJ, De Leon-Rodriguez A, Bañuelos JA, Alvarez-Contreras L, Guerra-Balcázar M, Arjona N. "Electrocatalytic oxidation of sorbitol on PdxAuy/C bimetallic nanocatalysts.". FUEL . 2022;

314 : 122788

5.- Vazquez Rodriguez G, Juvera Avalos ER, Gonzalez C, Barba de la Rosa AP, and De Leon-Rodriguez A. "Production and optimization of a vasostatin-30 and vasoinhibin fusion protein that inhibits tumor angiogenesis and dissemination of breast cancer cells in a zebrafish model. ". PROCESS BIOCHEMISTRY . 2022;

(en impresión (aceptado))

6.- Balderas-Hernández VE, Medina-Rivero E, Barba-De la Rosa AP, De León-Rodríguez A. "Agave salmiana syrup improves the production of recombinant human interleukin-2 in Escherichia coli". REVISTA MEXICANA DE INGENIERÍA QUÍMICA . 2021;

1 : 399-412

7.- Balderas Hernandez VE, Salas-Montante CJ, Barba-De la Rosa AP, De Leon-Rodriguez A "Autodisplay of an endo-1,4-beta-xylanase from Clostridium cellulovorans in Escherichia coli for xylans degradation". ENZYME AND MICROBIAL TECHNOLOGY . 2021;

149 : 109834

8.- Pereyra-Camacho MA, Balderas-Hernadez VE, De Leon-Rodriguez A "Biodegradation of diisononyl phthalate by a consortium of saline soil 7 bacteria: optimisation and kinetic characterisation". APPLIED MICROBIOLOGY AND BIOTECHNOLOGY . 2021;

105 : 3369-3380

9.- Lopez-Hidalgo AM, Magaña G, Rodriguez F, De León-Rodríguez A, Sanchez A. "Co-production of ethanol-hydrogen by genetically engineered Escherichia coli insustainable biorefineries for lignocellulosic etanol production. ". CHEMICAL ENGINEERING JOURNAL . 2021;

406 : 126829

10.- Guzmán-Albores JM, Bojórquez-Velázquez E, De León-Rodríguez A, Calva-Cruz OJ, Barba de la Rosa AP, Ruíz-Valdiviezo VM "Comparison of Moringa oleifera oils extracted with supercritical fluids and hexane and characterisation of seed storage proteins in defatted flour". FOOD BIOSCIENCE . 2021;

40 : 1-11

11.- Lopez-Hidalgo AM, Balderas Hernandez VE, De Leon-Rodriguez A "Scale-up of hydrogen and ethanol co-production by an engineered Escherichia coli". FUEL . 2021;

300 : 121002

12.- Sanchez A, Ayala OR, Hernandez-Sanchez P, Valdez-Vazquez I, De León-Rodríguez A. "An environment-economic analysis of hydrogen production using advanced biorefineries and its comparison with conventional technologies". INTERNATIONAL JOURNAL OF HYDROGEN ENERGY . 2020;

45(51) : 27994-28006

13.- Gutiérrez-García AK, Alvarez-Guzmán CL and De Leon-Rodriguez A. "Autodisplay of alpha amylase from Bacillus megaterium in E. coli for the bioconversion of starch into hydrogen, ethanol and succinic acid.". ENZYME AND MICROBIAL TECHNOLOGY . 2020;

134 : 109477

14.- González-Escobar JL, Pereyra-Camacho MA, De León-Rodríguez A, Grajales-Lagunes A, Reyes-Agüero A, Chagolla-López A, Barba de la Rosa AP "Biodegradation of recalcitrant compounds and phthalates by cultural bacteria isolated form Liometopum apiculatum microbiota". WORLD JOURNAL OF MICROBIOLOGY & BIOTECHNOLOGY . 2020;

36 : 1-13

15.- Alvarez-Guzmán CL, Cisneros-de la Cueva S, Balderas-Hernández VE, Smoliński A, De Leon Rodriguez A. "Biohydrogen production from cheese whey powder by Enterobacter asburiae: Effect of operating conditions on hydrogen yield and chemometric study of the fermentative metabolites". ENERGY REPORTS . 2020;

6 : 1170-1180

16.- Alvarez-Guzmán CL, Balderas-Hernández VE, De Leon Rodriguez A. "Coproduction of hydrogen, ethanol and 2,3-butanediol from agro-industrial residues by the Antarctic psychrophilic GA0F bacterium". INTERNATIONAL JOURNAL OF HYDROGEN ENERGY . 2020;

45 : 26179-26187

17.- Balderas-Hernández VE, Ornelas-Salas JT, Barba de la Rosa AP, De Leon-Rodriguez A "Diminution of miigration of phthalic acid esters in tequila beverage by the year of production". JOURNAL OF ENVIRONMENTAL SCIENCE AND HEALTH PART B-PESTICIDES FOOD CONTAMINANTS AND AGRICULTURAL WASTES . 2020;

55(2) : 148-154

18.- Jiang T, Munguia-Lopez JG, Gu K,Bavoux MM, Flores-Torres S, Kort-Mascort J, Grant J, Vijayakumar S, De Leon-Rodriguez A, Ehrlicher AJBand Kinsella JM "Engineering bioprintable alginate/gelatin composite hydrogels with tunable mechanical and cell adhesive properties to modulate tumor spheroid growth kinetics". BIOFABRICATION . 2020;

12 : 015024

19.- Balderas-Hernández VE, Landeros Maldonado KP, Sánchez A, Smolinski A, De León-Rodríguez A "Improvement of hydrogen production by metabolic engineering of Escherichia coli: modification on both the PTS system and central carbon metabolism". INTERNATIONAL JOURNAL OF HYDROGEN ENERGY . 2020;

20 : 5687-5696

20.- Torres-Pacheco, L.J., De Leon-Rodriguez, A., Álvarez-Contreras, L., Guerra-Balcázar, M., Arjona, N "Sorbitol electro-oxidation reaction on sub". ELECTROCHIMICA ACTA . 2020;

353 : 136593

21.- Jose G Munguia-Lopez, Rodrigo Juarez, Emilio Muñoz-Sandoval, Marco A Kalixto-Sanchez, Joseph Matthew Kinsella, Antonio De Leon-Rodriguez "Biocompatibility of nitrogen-doped multiwalled carbon nanotubes with murine fibroblasts and human hematopoietic stem cells". JOURNAL OF NANOPARTICLE RESEARCH . 2019;

21(8) : 193

22.- Oceguera-Contreras E., Aguilar-Juárez O., Oseguera-Galind D., Macías-Barragán J., Bolaños-Rosales R, Mena-Enríquez M., Arias-García A., Montoya-Buelna M., Graciano-Machuca O.n and De León-Rodríguez A. "Biohydrogen production by vermihumus-associated microorganisms using agroindustrial wastes as substrate". INTERNATIONAL JOURNAL OF HYDROGEN ENERGY . 2019;

44 : 9856-9865

23.- Gutiérrez-García AK, Choundhury M, De Leon Rodriguez A. "Diisononyl Phthalate differentially affects sirtuin expression in the HepG2 cell line.". CHEMICAL RESEARCH IN TOXICOLOGY . 2019;

37 : 449-457

24.- Pérez-Sariñana BY, Díaz-González A, De León-Rodriguez A, Saldaña-Trinidad S, Pérez-Luna YC, Guerrero-Fajardo CA, P.J. Sebastian "Methane production from coffee crop residues.". ROMANIAN BIOTECHNOLOGICAL LETTERS . 2019;

24 : 669-675

25.- Olguín-Calderón D, González-Escobar JL, Ríos-Villa R, Dibildox-Alvarado E, De Léon-Rodríguez A, Barba de la Rosa AP "Modulation of caecal microbiome in obese mice associated with administration of amaranth or soybean protein isolates". POLISH JOURNAL OF FOOD AND NUTRITION SCIENCES . 2019;

69 : 35-44

26.- Gutiérrez-García AK, Flores-Kelly JM, Ortiz-Rodríguez T, Kalixto Sánchez MA, De León-Rodríguez A "Phthalates affect the in vitro expansion of human hematopoietic cells". CYTOTECHNOLOGY . 2019;

71 : 553-561

27.- Lopez-Hidalgo AM, Alvarado-Cuevas ZD, De León-Rodríguez A "Biohydrogen production from mixtures of agro-industrial wastes: chemometric analysis, optimization and scaling up". ENERGY . 2018;

159 : 32-41

28.- 1. Calderon-Salais S, Velazquez-Bernardino P, Balderas-Hernandez VE, Barba de la Rosa AP, De Leon-Rodriguez A. "Constitutive expression of the active fragment of human vasostatin Vs30 in Pichia pastoris SMD1168H.". PROTEIN EXPRESSION AND PURIFICATION . 2018;

144 : 40-45

29.- Cisneros de la Cueva S, Álvarez Guzmán CL, Balderas-Hernández VE, De León Rodríguez A "Optimization of biohydrogen production by the novel psychrophilic strain N92 collected from the Antarctica.". INTERNATIONAL JOURNAL OF HYDROGEN ENERGY . 2018;

43 : 13798-13809

30.- Jiang T, Munguia-Lopez, Flores Torres S, JG, Grant J, Vijayakumar S, De Leon Rodriguez A, Kinsella J. "Directing the Self-assembly of Tumour Spheroids by Bioprinting Cellular Heterogeneous Models within Alginate/Gelatin Hydrogels". SCIENTIFIC REPORTS . 2017;

7 : 4575

31.- Alvarez-Guzmán CL, Balderas-Hernández VE, González-García R, Ornelas-Salas JT, Vidal-Limón AM, Cisneros-de la Cueva S, De Leon-Rodriguez A "Optimization of hydrogen production by the psychrophilic strain G088". INTERNATIONAL JOURNAL OF HYDROGEN ENERGY . 2017;

42(6) : 3630¿3640

32.- Lopez-Hidalgo AM, Sanchez A, De Leon-Rodriguez A "Simultaneous production of bioethanol and biohydrogen by Escherichia coli WDHL using wheat straw hydrolysate as substrate". FUEL . 2017;

188 : 19-27

33.- Alvarez-Guzman CL, Oceguera-Contreras E, Ornelas-Salas JT, Balderas Hernandez VE, De Leon-Rodriguez A "Biohydrogen production by the psychrophilic G088 strain using single carbohydrates as substrate". INTERNATIONAL JOURNAL OF HYDROGEN ENERGY . 2016;

41 : 8092-9100

34.- Campos-Delgado J, Castro KLS, Munguia-Lopez JG, Gonzalez AK, Mendoza ME, Fragneaud B, Verdan R, Araujo JR, Gonzalez FJ, Navarro-Contreras H, Perez-Maldonado IN, De Leon Rodriguez A, Achete CA "Effect of graphene oxide on bacteria and peripheral blood mononuclear cells". JOURNAL OF APPLIED BIOMATERIALS & FUNCTIONAL MATERIALS . 2016;

14(4) : 423-430

35.- De Leon-Rodriguez A, Caño-Muñiz SL, Liu J, Summers DK "Indole modifies the central carbon flux in the anaerobic metabolism of Escherichia coli: application to the production of hydrogen and other metabolites.". NEW BIOTECHNOLOGY . 2016;

33 : 868-873

36.- Montero-Morán GM, Sampedro JG, Saab-Rincón G, Cervantes-González MA, Huerta-Ocampo JA, De León-Rodríguez A, Barba de la Rosa AP "Biochemical and Molecular Characterization of a novel Cu/Zn Superoxide Dismutase from Amaranthus hypochondriacus L.: an Intrinsically Disordered Protein". APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY . 2015;

176 : 2328-2345

37.- Alvarado-Cuevas ZD, López-Hidalgo AM, Ordoñez LG, Oceguera-Contreras E, Ornelas Salas JT, and De León-Rodríguez A. "Biohydrogen production using psychrophilic bacteria isolated from Antarctica. (http://authors.elsevier.com/a/1R40M1HxM4Uo-i)". INTERNATIONAL JOURNAL OF HYDROGEN ENERGY . 2015;

40 : 7586-7592

38.- Munguía-Lopez JG, Muñoz-Sandoval E, Ortiz-Medina J, Rodriguez-Macias JF, and De Leon-Rodriguez A. "Effects of Nitrogen-Doped Multiwall Carbon Nanotubes on Murine Fibroblasts". JOURNAL OF NANOMATERIALS . 2015;

(en impresión (aceptado))

39.- Rosales Colunga LM, De Leon Rodriguez A "Escherichia coli and its application to biohydrogen production". REVIEWS IN ENVIRONMENTAL SCIENCE AND BIO/TECHNOLOGY . 2015;

14 : 123-135

40.- Rojas-Contreras JA, Barba de la Rosa AP, De Leon Rodriguez A "Expression and characterization of a recombinant psychrophilic Cu/Zn Superoxide Dismutase from Deschampsia antarctica E. Desv. [Poaceae]". APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY . 2015;

175 : 3287¿3296

41.- Pérez-Sariñana BY, De León-Rodriguez A, Saldaña-Trinidad S, Pathiyamattom Joseph S. "Optimization of Bioethanol Production from Coffee Mucilage". BIORESOURCES . 2015;

10 : 4326-4338

42.- Joaquín-Ramos A, Huerta-Ocampo JA, Barrera-Pacheco A, De León-Rodríguez A, Baginsky S, Barba de la Rosa AP "Comparative proteomic analysis of amaranth mesophyll and bundle sheath chloroplasts and their adaptation to salt stress". JOURNAL OF PLANT PHYSIOLOGY . 2014;

171 : 1423-1435

43.- Andrade-Zaldivar H, Kalixto-Sanchez MA, Barba de La Rosa AP and De Leon-Rodriguez A. "Expansion of CD34+ human hematopoietic cells from umbilical cord blood using roller bottles". REVISTA MEXICANA DE INGENIERIA QUIMICA . 2014;

13(2) : 379-385

44.- Perez-Martinez AS, Barba de La Rosa AP and De Leon-Rodriguez A "Heterologous expression of Trichoderma atroviride endochitinase ech42 in Pichia pastoris at low and high dissolved oxygen tensions". REVISTA MEXICANA DE INGENIERIA QUIMICA . 2014;

13(1) : 93-101

45.- Gonzalez-Castro MI, Ordoñez-Acevedo LG, Herrera-Vazquez Y, Ramirez-Telles JA, De Leon-Rodriguez A "Analysis of phthalic acid, bisphenol a and bisphenol a dimethacrylate in mexican food cans by hplc with evaporative light scattering detector". ACTA ALIMENTARIA . 2013;

42 : 97-103

46.- Rosales-Colunga LM, Alvarado-Cuevas ZD, Razo-Flores E, De Leon Rodriguez A "Maximizing Hydrogen Production and Substrate Consumption by Escherichia coli WDHL in Cheese Whey Fermentation". APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY . 2013;

171 : 704-715

47.- Carrazco-Peña L, Osuna-Castro JA, De Leon Rodriguez, Maruyama N, Toro-Vazquez J, Morales-Rueda J, Barba De La Rosa AP "Modification of solubility and heat induced gelation of amaranth 11S globulin by protein engineering". JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY . 2013;

61 : 3509-3516

48.- Alvarado-Cuevas ZD, Ordoñez Acevedo LG, Ornelas Salas JT, De León-Rodríguez A "Nitrogen sources impact hydrogen production by Escherichia coli using cheese whey as substrate". NEW BIOTECHNOLOGY . 2013;

30 : 585-590

49.- Vazquez Rodriguez G, Gonzalez C, De Leon Rodriguez A "Novel Fusion Protein Derived from Vasostatin 30 and Vasoinhibin II-14.1 Potently Inhibits Coronary Endothelial Cell Proliferation". MOLECULAR BIOTECHNOLOGY . 2013;

54 : 920-929

50.- Rosales- Colunga LM, Razo E, De Leon Rodriguez A "Fermentation of lactose and its constituent sugars by E. coli WDHL: Impact on hydrogen production". BIORESOURCE TECHNOLOGY . 2012;

111 : 180-184

51.- Barba de la Rosa AP, Briones-Cerecero E, Lugo-Melchor O, De León-Rodríguez A, Santos L, Castelo-Ruelas J, Valdivia A, Piña P, Chagolla-López A, Hernández-Cueto D, Mantilla A, Lazos-Ochoa M, Gonzalez-Yebra B, Salcedo M. "Hox B4 as potential marker of non-differentiated cells in human cervical cancer cells". JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY . 2012;

138 : 293-300 Número de citas: 3

52.- Huerta-Ocampo JA, Osuna-Castro JA, Lino-López GJ, Barrera-Pacheco A, Mendoza-Hernández G, De León-Rodríguez A, Barba de la Rosa AP "Proteomic analysis of differentially accumulated proteins during ripening and in response to 1-MCP in papaya fruit". JOURNAL OF PROTEOMICS . 2012;

75 : 2160-2169 Número de citas: 17

53.- García-Echauri SA, Gidekel M, Gutierrez- Moraga A, Santos L, De Leon Rodriguez A " Isolation and phylogenetic classification of culturable psychrophilic prokaryotes from the Collins glacier in the Antarctica". FOLIA MICROBIOLOGICA . 2011;

56 : 209-214

54.- Andrade-Zaldivar H, Kalixto-Sánchez MA, Barba de la Rosa AP, De León Rodriguez A "Expansion of human hematopoietic cells from umbilical cord blood using roller bottles in CO2 and CO2 free atmosphere". STEM CELLS AND DEVELOPMENT . 2011;

20(4) : 593-598

55.- Leticia Santos, Ma Fabiola León-Galvan, Cornelia Fuentes-Ahumada, Erika Nahomy Marino-Marmolejo, Antonio De León-Rodríguez, Ana Paulina Barba De La Rosa, Rebeca Ceballos-Salazar, Bertha Torres-Alvarez, Benjamín Moncada-González "HLA-Cw and TCR vβ analysis in twenty Mexican patients with Psoriasis ". CENTRAL EUROPEAN JOURNAL OF MEDICINE . 2011;

6(4) : 442-448

56.- Aguilar-Hernández HS, Santos L, León-Galván MF, Barrera-Pacheco A, Espitia-Rangel E, De León-Rodrígez A, Guevara-González RG, Barba de la Rosa AP "Identification of calcium stress induced genes in amaranth leaves through suppression subtractive hybridization ". JOURNAL OF PLANT PHYSIOLOGY . 2011;

168 : 2102-2109 Número de citas: 3

57.- Leticia Santos, Ma. Fabiola León-Galván, Erika Nahomy Marino-Marmolejo, Ana Paulina Barba de la Rosa, Antonio De León Rodríguez, Roberto González-Amaro, Ramón Gerardo Guevara-González "Identification of differential expressed transcripts in cervical cancer of Mexican patients ". TUMOR BIOLOGY . 2011;

32 : 561-568. Número de citas: 1

58.- MI González-Castro, MF Olea-Serrano, AM Rivas-Velasco, E Medina-Rivero, LG Ordoñez and A De León-Rodríguez "Phthalates and bisphenols migration in Mexican food cans and plastic food containers". BULLETIN OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY . 2011;

86 : 627-631

59.- Davila-Vazquez, G., de León Rodríguez, A., Alatriste-Mondragón, F., Razo-Flores, E. "The buffer composition impacts the hydrogen production and the microbial community composition in non-axenic cultures". BIOMASS & BIOENERGY . 2011;

35(7) : 3174-3181

60.- Huerta-Ocamo JA, León-Galván MF, Ortega-Cruz LB, Barrera-Pacheco A, De León-Rodríguez A, Mendoza-Hernández G, Barba de la Rosa AP "Water stress induces the up-regualtion of DOF1 and MIF1 transcription factors and down-regulation of proteins involved in secondary metabolism in amaranth roots (Amaranthus hypochondriacus L.)". PLANT BIOLOGY . 2011;

13 : 472-482 Número de citas: 11

Publicaciones en otros índices internacionales

1.- Jiang T, Lopez-Munguia JG, Flores-Torres S, Grant J, Vijayakumar S, De Leon Rodriguez A, Kinsella JS. "Bioprintable Alginate/Gelatin Hydrogel 3D In Vitro Model Systems Induce Cell Spheroid Formation". J Vis Exp . 2018;

: 137

2.- Barba de la Rosa AP, Lugo-Melchor OY, Briones-Cerecero EP, Chagolla-López A, De León-Rodríguez A, Santos L, Vázquez-Ortiz G, Salcedo M "Analysis of human serum from women affected by cervical lesions". The Journal of Experimental Therapeutics and Oncology . 2008;

7 : 65-72 Número de citas: 4

3.- De León, A., Cortés, G., Ramírez, O.T. y Galindo, E. "Diseño, caracterización y aplicación de un simulador de gradientes de oxígeno disuelto presentes en fermentadores de gran escala". Avanc. Ing. Quimica . 1995;

5 (1) : 1-6

4.- De León, A. , Galindo, E., y Ramírez, O.T. "Effect of oscillating dissolved oxygen tension on penicillin acylase production by a recombinant E. coli". Biochem. Eng. . 1995;

3 : 200-202

Publicaciones en revistas no indizadas

1.-Escalante-Minakata P, Barba de la Rosa AP, Santos L, De León-Rodríguez A "Aspectos Químicos y Moleculares del Proceso de Producción del Mezcal". BioTecnología . 2012;

16 : 57-70

2.-P. Escalante Minakata, L. González Hernández, A.P. Barba de la Rosa, A. De León Rodríguez "El mezcal, una mezcla natural de alcoholes y feromonas". Bebidas mexicanas . 2006;

15(3) : 10-18